Yale University

The Center for Neuroscience and Regeneration Research of Yale houses a multidisciplinary research team (molecular and cell biologists, electrophysiologists, biophysicists, pharmacologists, pain physiologists) who work collaboratively to build upon the molecular revolution, with the goal of finding new therapies for disorders of the nervous system with a focus on neuropathic pain.

The Center possesses unique expertise in molecular biology and functional profiling of ion channels and variants expressed within DRG neurons.

Specialized equipment available for this research include: an imaging core (includes an electron microscope, Two-photon confocal microscope, two standard confocal microscopes, two setups for live imaging of Calcium sensitive dyes); fully equipped molecular biology labs including robotic liquid handling, real-time PCR (2), digital PCR; electrophysiology core (seven fully equipped patch-clamp rigs, two automated platforms, multielectrode array setup) and spinal cord recording set-ups); tissue culture rooms (3); animal housing facility and a surgery suite for survival surgeries; computational core for structural modelling.

Staff has access to Yale core facilities (genomics, proteomics and imaging), libraries and educational activities including weekly seminars, periodic symposia and workshops.

Staff members

Stephen G. Waxman

Supervisor of ESR 9

Expertise

Molecular and cellular neuroscience, Electrophysiology, Neurogenetics, whole animal studies. Member of National Academy of Medicine and multiple societies including SFN, AAN, ANA, and others. Editor-in-Chief of Neuroscience Letters and The Neuroscientist.

More than 600 papers in international peer reviewed journals.

Director of the Center for Neuroscience and Regeneration Research (CNRR). He is the Bridget Flaherty Professor of Neurology, Neurobiology and Pharmacology, and the immediate past Chairman of the Dept. of Neurology at Yale University. The Center has more than 35 scientific staff at different levels of seniority.

Sulayman D. Dib-Hajj

Co-supervisor of ESR 9

Expertise

Molecular and cellular neuroscience, electrophysiology, neurogenetics, animal studies. Member in several societies including SFN, ABSMB, IASP. Member of the scientific advisory board of the Paralyzed Veterans of America; member of the Board of Directors for the National Disease Research Interchange, USA.

More than 170 papers in international peer reviewed journals.

Associate Director of the Center for Neuroscience and Regeneration Research and Senior Research Scientist at Yale University. Supervisor of more than 10 postdocs, 2 Ph.D. students, and core staff.